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Baoling Ying Selected Research

Adenoviridae Infections (Adenovirus Infections)

1/2019Drug development against human adenoviruses and its advancement by Syrian hamster models.
1/2018Characterization of an N-Terminal Non-Core Domain of RAG1 Gene Disrupted Syrian Hamster Model Generated by CRISPR Cas9.
1/2018Male Syrian hamsters are more susceptible to intravenous infection with species C human adenoviruses than are females.
10/2017Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds.
1/2017HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.
8/2015STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.
3/2015Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters.
12/2014Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.
7/2003Mutations within the ADP (E3-11.6K) protein alter processing and localization of ADP and the kinetics of cell lysis of adenovirus-infected cells.

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Baoling Ying Research Topics

Disease

22Infections
02/2022 - 07/2003
9Adenoviridae Infections (Adenovirus Infections)
01/2019 - 07/2003
5COVID-19
02/2022 - 01/2021
3Weight Loss (Weight Reduction)
02/2022 - 08/2021
3Breakthrough Infections
02/2022 - 08/2021
2Inflammation (Inflammations)
02/2022 - 01/2022
2Pneumonia (Pneumonitis)
02/2022 - 08/2021
2Neoplasms (Cancer)
12/2015 - 05/2004
1Human Influenza (Influenza)
01/2022
1Bites and Stings (Sting)
01/2021
1Body Weight (Weight, Body)
10/2020
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/2018
1Human Adenovirus Infections
09/2017
1DNA Virus Infections
01/2017
1Breast Neoplasms (Breast Cancer)
12/2015
1Virus Diseases (Viral Diseases)
08/2015
1Herpesviridae Infections (Herpesvirus Infection)
12/2014
1Colonic Neoplasms (Colon Cancer)
05/2004

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
02/2022 - 07/2003
8VaccinesIBA
02/2022 - 01/2021
5Antiviral Agents (Antivirals)IBA
01/2022 - 11/2015
4mRNA VaccinesIBA
02/2022 - 08/2021
4Pharmaceutical PreparationsIBA
01/2018 - 12/2014
3Neutralizing AntibodiesIBA
02/2022 - 01/2018
32019-nCoV Vaccine mRNA-1273IBA
02/2022 - 01/2022
3ValganciclovirFDA Link
10/2017 - 03/2015
3Adenosine Diphosphate (ADP)IBA
05/2004 - 07/2003
2Messenger RNA (mRNA)IBA
02/2022 - 11/2010
2brincidofovirIBA
10/2017 - 12/2014
2Cidofovir (Vistide)FDA Link
01/2017 - 12/2014
2Ganciclovir (Cytovene)FDA LinkGeneric
03/2015 - 12/2014
1Monoclonal AntibodiesIBA
01/2022
1Influenza Vaccines (Influenza Vaccine)FDA Link
01/2022
1N-methyl-valyl-amiclenomycin (BA 2)IBA
01/2022
1Ad26COVS1IBA
01/2022
1CytokinesIBA
01/2022
1N-(2-cyanoethylene)urea (BA 1)IBA
01/2022
1LigandsIBA
01/2021
1MicroRNAs (MicroRNA)IBA
09/2017
1TristetraprolinIBA
12/2015
1thiamine triphosphorate (TTP)IBA
12/2015
1RNA-Binding Proteins (RNA-Binding Protein)IBA
12/2015
1Interferon Type IIBA
08/2015
1InterferonsIBA
08/2015
1Ribavirin (Virazole)FDA LinkGeneric
12/2014
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2014
1DNA (Deoxyribonucleic Acid)IBA
11/2010
1DNA-Binding Proteins (DNA Binding Protein)IBA
12/2007
1beta CateninIBA
05/2004
1Glycoproteins (Glycoprotein)IBA
07/2003

Therapy/Procedure

4Therapeutics
04/2021 - 10/2017
1Oral Administration
10/2020
1Immunotherapy
01/2019
1Intravenous Injections
01/2018
1Hematopoietic Stem Cell Transplantation
01/2018
1Off-Label Use
01/2017